pharmgkb-annotator

PharmGKB pharmacogenomics annotation skill for drug-gene interaction assessment

509 stars

Best use case

pharmgkb-annotator is best used when you need a repeatable AI agent workflow instead of a one-off prompt.

PharmGKB pharmacogenomics annotation skill for drug-gene interaction assessment

Teams using pharmgkb-annotator should expect a more consistent output, faster repeated execution, less prompt rewriting.

When to use this skill

You want a reusable workflow that can be run more than once with consistent structure.

When not to use this skill

You only need a quick one-off answer and do not need a reusable workflow.
You cannot install or maintain the underlying files, dependencies, or repository context.

Installation

Claude Code / Cursor / Codex

$curl -o ~/.claude/skills/pharmgkb-annotator/SKILL.md --create-dirs "https://raw.githubusercontent.com/a5c-ai/babysitter/main/library/specializations/domains/science/bioinformatics/skills/pharmgkb-annotator/SKILL.md"

Manual Installation

Download SKILL.md from GitHub
Place it in .claude/skills/pharmgkb-annotator/SKILL.md inside your project
Restart your AI agent — it will auto-discover the skill

How pharmgkb-annotator Compares

Feature / Agent	pharmgkb-annotator	Standard Approach
Platform Support	Not specified	Limited / Varies
Context Awareness	High	Baseline
Installation Complexity	Unknown	N/A

Frequently Asked Questions

What does this skill do?

PharmGKB pharmacogenomics annotation skill for drug-gene interaction assessment

Where can I find the source code?

You can find the source code on GitHub using the link provided at the top of the page.

SKILL.md Source

# PharmGKB Annotator Skill

## Purpose
Provide PharmGKB pharmacogenomics annotation for drug-gene interaction assessment.

## Capabilities
- Star allele calling (Stargazer)
- Diplotype determination
- CPIC guideline integration
- Drug recommendation generation
- Clinical annotation lookup
- Dosing guidance extraction

## Usage Guidelines
- Call star alleles accurately
- Determine diplotypes from genotypes
- Apply CPIC guidelines for dosing
- Generate actionable recommendations
- Review clinical annotations
- Document guideline versions

## Dependencies
- PharmGKB API
- Stargazer
- PharmCAT

## Process Integration
- Pharmacogenomics Analysis (pharmacogenomics-analysis)
- Clinical Variant Interpretation (clinical-variant-interpretation)

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