star-rnaseq-aligner

STAR alignment skill for splice-aware RNA-seq read mapping with comprehensive QC metrics

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Best use case

star-rnaseq-aligner is best used when you need a repeatable AI agent workflow instead of a one-off prompt.

STAR alignment skill for splice-aware RNA-seq read mapping with comprehensive QC metrics

Teams using star-rnaseq-aligner should expect a more consistent output, faster repeated execution, less prompt rewriting.

When to use this skill

  • You want a reusable workflow that can be run more than once with consistent structure.

When not to use this skill

  • You only need a quick one-off answer and do not need a reusable workflow.
  • You cannot install or maintain the underlying files, dependencies, or repository context.

Installation

Claude Code / Cursor / Codex

$curl -o ~/.claude/skills/star-rnaseq-aligner/SKILL.md --create-dirs "https://raw.githubusercontent.com/a5c-ai/babysitter/main/library/specializations/domains/science/bioinformatics/skills/star-rnaseq-aligner/SKILL.md"

Manual Installation

  1. Download SKILL.md from GitHub
  2. Place it in .claude/skills/star-rnaseq-aligner/SKILL.md inside your project
  3. Restart your AI agent — it will auto-discover the skill

How star-rnaseq-aligner Compares

Feature / Agentstar-rnaseq-alignerStandard Approach
Platform SupportNot specifiedLimited / Varies
Context Awareness High Baseline
Installation ComplexityUnknownN/A

Frequently Asked Questions

What does this skill do?

STAR alignment skill for splice-aware RNA-seq read mapping with comprehensive QC metrics

Where can I find the source code?

You can find the source code on GitHub using the link provided at the top of the page.

SKILL.md Source

# STAR RNA-seq Aligner Skill

## Purpose
Provide STAR alignment for splice-aware RNA-seq read mapping with comprehensive QC metrics.

## Capabilities
- Splice junction detection
- Two-pass alignment mode
- Chimeric read detection (fusions)
- Gene quantification (--quantMode)
- Custom genome index generation
- Output in multiple formats

## Usage Guidelines
- Generate genome indices with annotation
- Use two-pass mode for novel junction discovery
- Enable chimeric read detection for fusion analysis
- Generate quantification in addition to alignments
- Optimize parameters for read length
- Document STAR version and parameters

## Dependencies
- STAR
- HISAT2
- kallisto

## Process Integration
- RNA-seq Differential Expression Analysis (rnaseq-differential-expression)
- Single-Cell RNA-seq Analysis (scrnaseq-analysis)
- Spatial Transcriptomics Analysis (spatial-transcriptomics)